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#effectiveness

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Luca Minudel

...

- a new normal of rapid innovation/change therefore complexity, unpredictabilities, uncertainties, and disorder

- a need for a new way of thinking about work, not frameworks

- the primary role played by the human element

- The value of lessons learned from leading-edge lightweight software & product development

AUTHOR NAMES YOU'D SUGGEST?

#Productivity
#Effectiveness
#ReinventingOrganisations
#PostTaylorism
#PostFordism
#ParadigmShift
#ComplexityThinking
#VibeCoding
#CHOP
#NOCODE

Public
Jason Gorman

Much of the #effectiveness in software dev comes from working backwards. Start at the outcome.

e.g.,

* working backwards from the deployment environment to the developers' machines

* working backwards from test assertions to test set-ups

* working backwards from user outcomes to user journeys

Public
Giuseppe Michieli

#Effectiveness of #Pasteurization for #Inactivation of #H5N1 #Influenza Virus in Raw Whole #Milk, MedRxIV: medrxiv.org/content/10.1101/20

Complete inactivation was achieved after incubation of H5N1 spiked raw milk at 63C for 30 min. Complete viral inactivation was observed in 7 out of 8 replicates of raw milk samples treated at 72C for 15 sec. In 1 replicate, a 4.56 log reduction was achieved, which is about 1 log higher than average viral quantities detected in bulk tanks in affected areas.

medRxiv · Effectiveness of Pasteurization for the Inactivation of H5N1 Influenza Virus in Raw Whole MilkHighly pathogenic avian influenza (HPAI) clade 2.3.4.4b H5Nx viruses continue to cause episodic incursions and have been detected in more than 12 taxonomic orders encompassing more than 80 avian species, land and marine mammals, including recent detections in dairy cattle. The HPAI H5N1 spillover to these important livestock species creates a new interface for human exposure and raises food safety concerns. Presence of H5N1 genetic material in one out of five retail pasteurized milk samples in the USA has prompted the evaluation of pasteurization processes for the inactivation of influenza viruses. Our study examined whether pasteurization could effectively inactivate HPAI H5N1 inoculated raw whole milk samples. We heated 1 mL of non-homogenized cow’s milk samples to attain an internal temperature of 63°C or 72°C and spiked with 6.3 log EID50 of clade 2.3.4.4b H5N1 virus. Complete inactivation was achieved after incubation of the H5N1 spiked raw milk at 63°C for 30 minutes. In addition, complete viral inactivation was observed in seven out of eight replicates of raw milk samples treated at 72°C for 15 seconds. In one replicate, a 4.56 log reduction was achieved, which is about 1 log higher than the average viral quantities detected in bulk tanks in affected areas. Therefore, we conclude that pasteurization of milk is an effective strategy for mitigation of risk of human exposure to milk contaminated with H5N1 virus. ### Competing Interest Statement The authors have declared no competing interest. ### Funding Statement Canadian Food Inspection Agency Health Canada ### Author Declarations I confirm all relevant ethical guidelines have been followed, and any necessary IRB and/or ethics committee approvals have been obtained. Yes I confirm that all necessary patient/participant consent has been obtained and the appropriate institutional forms have been archived, and that any patient/participant/sample identifiers included were not known to anyone (e.g., hospital staff, patients or participants themselves) outside the research group so cannot be used to identify individuals. Yes I understand that all clinical trials and any other prospective interventional studies must be registered with an ICMJE-approved registry, such as ClinicalTrials.gov. I confirm that any such study reported in the manuscript has been registered and the trial registration ID is provided (note: if posting a prospective study registered retrospectively, please provide a statement in the trial ID field explaining why the study was not registered in advance). Yes I have followed all appropriate research reporting guidelines, such as any relevant EQUATOR Network research reporting checklist(s) and other pertinent material, if applicable. Yes All data produced in the present study are available upon reasonable request to the authors
Continued thread
Public
João Rosa

🌱 And what is the alternative, you may ask. The alternative is to respect our nature and understand that we are open systems. The organizational structure should match, which means that the organizational design should involve the people who are part of the organization! In that way, the operating model will focus on #effectiveness, which respects our nature and leverages what we are best at finding creative solutions for challenges. Together. As a group.

3/

Public
Giuseppe Michieli

Link-Gelles R, Ciesla AA, Mak J, et al. Early #Estimates of Updated 2023–2024 (Monovalent #XBB15) #COVID19 #Vaccine #Effectiveness Against Symptomatic #SARS-CoV-2 #Infection Attributable to Co-Circulating #Omicron Variants Among Immunocompetent Adults — Increasing Community Access to Testing Program, #USA, Sept 2023–Jan 2024. MMWR Morb Mortal Wkly Rep 2024;73:77–83. DOI: dx.doi.org/10.15585/mmwr.mm730

Centers for Disease Control and Prevention · Early Estimates of Updated 2023–2024 (Monovalent XBB.1.5) ...By CDC
Public *
💧🌏 Greg Cocks

Advantages and Disadvantages of Remote Sensing - Understanding the Limits of a Powerful Technology
--
skywatch.com/advantages-and-di <-- shared technical article / opinion piece
--
Excellent points, which is why I shared - but one they kind of missed was misinterpretation... it is a natural system, so the algorithms and process to take EA data and interpret necessarily can never be 100% perfect, and nor should they be expected to be. Ground truthing and other checks & balances are a crucial part of any such interpretation.
[This post is not considered an endorsement of this specific company]
--
#GIS #spatial #mapping #remotesensing #earthobservation #advantages #disadvantages #opinionpiece #spatialanalysis #spatiotemporal #alldataisspatial #effectiveness #blackbox #tool #appliedscience #interpretation #limitations #challenges #usefulness #value #roi

graphic - remotesensing satellites in orbit
graphic / schematic - remotesensing - from RISE
photo - drone over a forestry / logging setting
graphic - trees 'seen' in a LiDAR point cloud
Public
Giuseppe Michieli

[Correspondence] Short-term #effectiveness of the #XBB15 updated #COVID19 #vaccine against #hospitalisation in #Denmark: a national cohort study thelancet.com/journals/laninf/

-- In summary, early results from cohort analyses with natl health registry data in indicate a high level of protection from XBB.1.5 vaccine, at least in short term; vaccination was associated with a 76·1% reduced risk of COVID-19 hospitalisation in a population vaccinated with a booster dose the previous season.

Public
Susan Larson ♀️🏳️‍🌈🏳️‍⚧️🌈

#HealthMinister Shane Reti leads a review of a 1980s #affirmativeaction program for #Māori and #Pasifika medical students, he personally benefitted from.

#ACTParty #leader #DavidSeymour calls it "#racialdiscrimination," while #supporters defend its #effectiveness, deeming the #review as pointless.

#Women #Transgender #LGBTQ #LGBTQIA #NewZealand #HigherEducation #IndigenousPeople #Conservatives #Extremism #Fascism #Hate #Bigotry #Discrimination #Homophobia #Transphobia

rnz.co.nz/news/in-depth/504971

RNZ · Health Minister Shane Reti responsible for review of ‘affirmative action’ scheme he graduated from in 1980sBy Ella Stewart
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